BioSpectrum employs its own unique technologies, as well as very well-known traditional technologies, to transform the NATURE into outstanding ingredients for personal care products. Every manufacturing process is carried out using advanced facilities including our Jeju branch. Jeju Island is the largest island in Korea with incomparably beautiful NATURE. Jeju Island is known to have the richest repository of NATURAL resources in Korea. AII of our ingredients developed in BioSpectrum are from plants grown in Jeju Island, except for the ones that are not native in Jeju Island. This is why our NATURAL ingredients are special and unique.

BioSpectrum pursues to care our NATURE. We strive to make our manufacturing processes to be eco-compatible. The quality of our products is controlled by following the safety and quality standards set up in our company and by respecting the regulatory guidelines in our every manufacturing process.

>> Patents, Registered (40 Patents)

1. Skin whitening composition containing arbutin and glucosidase as active ingredients
Registration No.: 10-0389983-0000; Registration Date: Jun 20, 2004
Korean application No.: KR10-2001-0001236/Filing Date: Jan 10, 2001

2. Multiple layered liposome and preparation method thereof
Registration No.: 10-0461458-0000; Registration Date: Dec 02, 2004
Korean application No.: KR10-2004-0062070/Filing Date: Aug 10, 2004

3. Method for producing a cosmetic composition containing L-ascorbic acid.
Registration No.: 10-0477716-0000; Registration Date: Mar 10, 2005
Korean application No.: KR10-2002-0014776/Filing Date: Mar 19, 2002

4. Cosmetic composition comprising asiaticoside
Registration No.: 10-0511994-0000; Registration Date: Dec 02, 2005
Korean application No.: KR10-2005-0033634/Filing Date: Apr 22, 2005

5. Cosmetic composition for reducing skin wrinkles comprising asiaticoside
Registration No.:10-0641302-0000; Registration Date: Oct 25, 2006
Korean application No.: KR10-2005-0051604/Filing Date: Jul 15, 2005

6. Nano liposome composition
Registration No.: 10-0603814-0000; Registration Date: July 14, 2006
Korean application No.: KR 10-2004-0016334/Filing Date: Mar 11, 2004

7. Composition for improving atopic dermatitis comprising magnolol and honokiol
Registration No.: 10-0699538-0000 ; Registration Date: Mar 19, 2007
Korean application No.: KR10-2005-0085771/Filing Date: Sep 14, 2005

8. Antimicrobial composition comprising natural plant extract
Registration No.: 10-0729831-0000; Registration Date: Jun 12, 2007
Korean application No.: KR10-2005-0114677/Filing Date: Nov 29, 2005

9. Expression vector with Penetratin as a fusion partner to enhance transdermal delivery of recombinant proteins
Registration No.: 10-0729830-0000; Registration Date: Jun 12, 2007
Korean application No.: KR10-2005-0024702/Filing Date: Mar 24, 2005

10. Composition for improving skin wrinkle comprising plant extracts
Registration No.: 10-0729832-0000; Registration Date: Jun 12, 2007
Korean application No.: KR10-2007-0011021/ Filing Date: Feb 02, 2007

11. Composition for improving skin wrinkle comprising plant extracts
Registration No.: 10-0729833-0000; Registration Date: Jun 12, 2007
Korean application No.: KR10-2007-0011023 / Filing Date: Feb 02, 2007

12. Methods for improving contents of physiological activated substances
Registration No.: 10-0762965-0000; Registration Date: Aug 24, 2007
Korean application No.: KR10-2006-0025865/Filing Date: Mar 21, 2006

13. Cosmetic compositions for anti-aging of skin comprising diosgenin and dioscin
Registration No.: 10-0782600-0000; Registration Date: Aug 29, 2007
Korean application No.: KR 10-2006-0087883/Filing Date: Sep 12, 2006

14. Naturotics.
Registration No.: 10-0782599-0000; Registration Date: Nov 07, 2007
Korean application No.: KR10-2006-0031609/Filing Date: Apr 04, 2006

15. Composition for improving skin wrinkle comprising extract from Hypochoeris L.
Registration No.: 10-0702461-0000; Registration Date: Mar 21, 2007
Korean application No.: KR10-2005-0093410/Filing Date: Oct 05, 2005

16. Composition for skin whitening comprising artemisinine
Registration No.:10-0795515-0000; Registration Date: Jan 10, 2008
Korean application No.: KR10-2007-0003238/Filing Date: Jan 11, 2007

17. Composition for ameliorating inflammation comprising pinosylvin and rosmarinic acid
Registration No.: 10-0795513-0000; Registration Date: Jan 10, 2008
Korean application No.: KR 10-2006-0054537/Filing Date: Jun 16, 2006

18. Skin care composition comprising the extract of Centella asiatica and Magnolia kobus.
Registration No.: 10-0795512-0000; Registration Date: Jan 10, 2008
Korean application No.: KR 10-2006-0045039/Filing Date: May 19, 2006

19. Composition for skin whitening containing diosgenin
Registration No.: 10-0795514-0000; Registration Date: Jan 10, 2008
Korean application No.: KR 10-2006-0063414/Filing Date: Jul 6, 2006

20. A composition comprising compounds of natural origin for damaged skin
Registration No.: 10-0812596-0000; Registration Date: Mar 05, 2008
Korean application No.: KR10-2006-0128500/Filing Date: Dec 15, 2006

21. Composition containing S-(-)-tulipalin B or Acetylated-S-(-)-tulipalin B.
Registration No.: 10-0808490-0000; Registration Date: Feb 22, 2008
Korean application No.: 10-2007-0039050/Filing Date: Apr 20, 2007.

22. A skin whitening compositions comprising natural plant extract
Registration No.: 10-0829831-0000; Registration Date: May 08, 2008
Korean application No.: KR 10-2006-0087880/Filing Date: Sep 12, 2006

23. Composition for improving wrinkle on skin comprising ethanol extract of Aralia elata as an efficient ingredient
Registration No.: 10-0829832-0000; Registration Date: May 08, 2008
Korean application No.: KR10-2006-0001051/Filing Date: Jan 04, 2006

24. Compositions for Ameliorating Symptom of Atopic Dermatitis
Registration No.: 10-0832332-0000; Registration Date: May 20, 2008
Korean application No.: KR 10-2007-0014549/Filing Date: Feb 12, 2007

25. Compositions for Improving Skin Conditions Comprising 慣-Bisabolol as an Active Ingredient
Registration No.: 10-0823533-0000; Registration Date: April 14, 2008
Korean application No.: KR 10-2007-0019899/Filing Date: Feb 27, 2007

26. Compositions for anti-obesity Comprising 慣-Bisabolol as an Active Ingredient
Registration No.: 10-0823537-0000; Registration Date: Apr 14, 2008
Korean application No.: KR 10-2008-0015203/Filing Date: Feb 20, 2008

27. Compositions for Stimulating Hair Growth Comprising 慣-Bisabolol as an Active Ingredient
Registration No.: 10-0823535-0000; Registration Date: Apr 14, 2008
Korean application No.: KR 10-2008-0015202/Filing Date: Feb 20, 2008

28. Reverse-Phase Multi-Lamella Vesicle Capturing Aqueous Physiologically Active Ingredients.
Registration No.: 10-0831627-0000; Registration Date: May 16, 2008
Korean application No.: KR 10-2006-0042326/Filing Date: May 11, 2006

29. Compositions for improving skin conditions comprising Breu branco essential oil as an active agent
Registration No.: 10-0845888-0000; Registration Date: Jul 07, 2008
Korean application No.: 10-2007-0036672/Filing Date: Apr 13, 2007

30. Compositions for Improving Skin Wrinkle Comprising Piperine as an Active Ingredient
Registration No.: 10-0846125-0000; Registration Date: Jul 08, 2008
Korean application No.: 10-2007-0031899/Filing Date: Mar 30, 2007

31. Agents for improving wrinkles on skin comprising Matrine or Its Oxidized Derivatives
Registration No.: 10-0862968-0000; Registration Date: Oct 06, 2008
Korean application No.: KR 10-2007-0017400/Filing Date 21 Feb., 2007

32. Agents for anti-obesity comprising Matrine or Its Oxidized Derivatives
Registration No.: 10-0862967-0000; Registration Date: Oct 06, 2008
Korean application No.: KR 10-2008-0056310/Filing Date 16 June, 2008

33. Compositions for Improving Skin Conditions Comprising Barbituric acid as an Active Ingredient
Registration No.: 10-0862969-0000; Registration Date: Oct 06, 2008
Korean application No.: 10-2007-0021397/Filing Date: Mar 05, 2007.

34. Compositions for Improving Skin Wrinkle Comprising Hyperine as an Active Ingredient
Registration No.: 10-0862957-0000; Registration Date: Oct 06, 2008
Korean application No.: 10-2007-0032676/Filing Date: Apr 03, 2007.

35. Composition for improving skin conditions comprising alum
Registration No.: 10-0863617-0000; Registration Date: Oct 08, 2008
Korean application No.: 10-2007-0038170/Filing Date: Apr 19, 2007.

36. Composition for improving skin conditions comprising protocatechuic acid
Registration No.: 10-0863618-0000; Registration Date: Oct 08, 2008
Korean application No.: 10-2007-0038470/Filing Date: Apr 19, 2007.

37. Skincare composition containing Brazilian pepper oil
Registration No.: 10-0848800-0000; Registration Date: Jul 22, 2008
Korean application No.: 10-2007-0036944/Filing Date: Apr 16, 2007.

38. Compositions for improving skin conditions comprising Crowberry extract
Registration No.: 10-0863614-0000; Registration Date: Oct 08, 2008
Korean application No.: 10-2007-0036816/Filing Date: Apr 16, 2007.

39. Skincare composition containing copaiba balsam oil
Registration No.: 10-0863616-0000; Registration Date: Oct 08, 2008
Korean application No.: 10-2007-0036983/Filing Date: Apr 16, 2007.

40. Skincare composition containing priprioca oil
Registration No.: 10-0863615-0000; Registration Date: Oct 08, 2008
Korean application No.: 10-2007-0036909/Filing Date 16 Apr., 2007

>> Patents, Pending (Abroad, 11 Patents)

1. Multiple layered liposome and preparation method thereof
Europe application No.: EP04748522.2
PCT application No.: PCT/KR2004/001989 /Filing Date: Aug 06, 2004

2. Expression vector with Penetratin as a fusion partner to enhance transdermal delivery of recombinant proteins
PCT application No.: PCT/KR2005/000872/Filing Date: Mar 25, 2005

3. Composition for inhibiting collagen degradation and promoting collagen synthesis comprising emodin
PCT application No.: PCT/KR2006/001550/Filing Date: Apr 25, 2006

4. Methods for improving contents of physiological activated substances
US application No.: US11/725,885

5. Naturotics
US application No.: US11/732,455

6. Composition for improving atopic dermatitis comprising magnolol and honokiol
US application No.: US11/717,265

7. Biphenyl Diol Derivatives and Compositions Comprising the Same as an Active.
PCT application No.: PCT/KR2007/003680/Filing Date: Jul 31, 2007

8. Composition for skin whitening containing diosgenin
PCT application No.: PCT/KR2008/000046/Filing Date: Jan 04, 2008

9. Composition for skin whitening comprising artemisinine
PCT application No.: PCT/KR2008/000136/Filing Date: Jan 09, 2008

10. A composition comprising compounds of natural origin for damaged skin
PCT application No.: PCT/KR2008/006604/Filing Date: Dec 17, 2007
US application No.: US 12/093,233

11. Composition containing S-(-)-tulipalin B or Acetylated-S-(-)-tulipalin B
US application No.: US 12/105,757

>> Patents, Pending (Domestic, 20 Patents)

1. Anti-inflammatory composition comprising natural plant extract
Korean application No.: KR10-2006-0013165/Filing Date: Feb 10, 2006

2. Inhibitor of IKK Kinase Comprising Rosmarinic Acid
Korean application No.: KR10-2006-0023684/Filing Date: Mar 14, 2006

3. Biphenyl Diol Derivatives and Compositions Comprising the Same as an Active
Ingredient
Korean application No.: KR 10-2007-0014548 /Filing Date: Feb 12, 2007

4. Compositions for Improving Skin Conditions Comprising Carvacrol as an Active Ingredient
Korean application No.: KR 10-2007-0017364/Filing Date: Feb 21, 2007

5. Composition for skin whitening or promoting hair growth comprising Gynostemma pentaphyllum extract and gypenoside isolated from the same
Korean application No.: 10-2007-0026571/Filing Date: Mar 19, 2007.

6. Composition containing ginsenoside Ro
Korean application No.: 10-2007-0025340/Filing Date: Mar 15, 2007.

7. Composition for improving skin conditions comprising Limonene
Korean application No.: 10-2007-0044743/Filing Date: May 08, 2007.

8. Compositions for improving skin conditions comprising andiroba oil as an active agent
Korean application No.: 10-2007-0036250/Filing Date 13 Apr., 2007

9. Multi-emulsified vesicles comprising a multilamellar liposome and phospholipid monolayer nanoliposome
Korean application No.: 10-2007-0054234/Filing Date: Jun 04, 2007.

10. Compositions for improving skin conditions comprising delphinidin as an active agent
Korean application No.: 10-2007-0049591/Filing Date: May 22, 2007.

11. Compositions for improving skin conditions comprising isorhamnetin as an active agent
Korean application No.: 10-2007-0049592/Filing Date: May 22, 2007.

12. Compositions for improving skin conditions comprising citral as an active agent
Korean application No.: 10-2007-0079532/Filing Date: Aug 08, 2007.

13. Skincare composition for anti-aging comprising flavanone
Korean application No.: 10-2007-0073251/Filing Date: Jul 23, 2007.

14. Skincare composition for anti-aging comprising flavone
Korean application No.: 10-2007-0073757/Filing Date: Jul 23, 2007.

15. Compositions for melanin induction containing purine derivatives
Korean application No.: 10-2007-0117590/Filing Date: Nov 17, 2007.

16. Skin whitening composition containing purine derivatives
Korean application No.: 10-2007-0117592/Filing Date: Nov 17, 2007.

17. Composition for inducing hair growth containing Boehmeria sieboldiana B1. Extract or apigenin
Korean application No.: 10-2007-0119374/Filing Date: Nov 21, 2007.

18. Composition for skin whitening containing Platycodin D
Korean application No.: 10-2007 0126513/Filing Date: Dec 07, 2007.

19. Composition for melanin induction containing hesperetin
Korean application No.: 10-2008-0022228/Filing Date: Mar 10, 2008.

20. A stem cell proliferation inducer/composition for stem cell culture system containing vegetable peptone without fetal bovine serum
Korean application No.: 10-2008-0030237/Filing Date: Apr 01, 2008.

21. Probucol as a skin whitening agent
Korean application No.: 10-2008-0030282/Filing Date: Apr 01, 2008.