Stabilization / Penetration
Encapsulation refers to a physicochemical or mechanical process to entrap a substance in a material in order to produce small particles that contain an active agent surrounded by a coating or shell. Encapsulation shell materials include a variety of polymers, carbohydrates, fats, and waxes, depending on the core materials. Encapsulation is often mentioned as a way to protect active ingredient against severe environmental factors. The goal of encapsulation is to create a micro-environment in which the active ingredient will survive during processing and be released at appropriate sites. The protection of bioactive compounds, such as vitamins, antioxidants, proteins, and lipids, may be achieved using several encapsulation technologies for the production of cosmetics with enhanced functionality and stability. The reasons for micro encapsulation are countless. In some cases, the core must be isolated from its surroundings, as in isolating vitamins from the deteriorating effects of oxygen, retarding evaporation of a volatile core, improving the handling properties of a sticky material, or isolating a reactive core from chemical attack.
Coenzyme Q10 is the best-known active ingredient in anti-aging products. The coenzyme is also known as ubiquinone, because the enzyme is produced by the body itself and is present throughout the entire body, where it has a vital role in cell respiration. It activates the skin's metabolism and is also a free-radical scavenger, like vitamin E. When Q10 levels decrease with age, additional intake can reactivate the metabolism, which counteracts the effects of aging on the skin. It can be absorbed through the skin from cosmetics. Nutritional supplements containing coenzyme Q10 are already available in the USA. However, pure coenzyme Q10 is unstable and rarely water-soluble, making it difficult to use and absorb. When coenzyme Q10 is encapsulated in an inclusion complex with cyclodextrins, dispersion is produced from which the coenzyme Q10 can be more easily absorbed by the body.
BioSpectrum uses a biocompatible polymer shell to protect the material inside to enhance the stability of the material in nano/micro size capsules. Vitamin C Core-Shell uses silicon polymer to protect unstable substance as vitamin C. (Figure 1)
·Registration No.:10-0461458-0000; Registration Date: 02. Dec. 2004.
·Registration No.:10-0603814-0000; Registration Date: 14. July. 2006.
·Registration No.: 10-0831627-0000; Registration Date: 16. May. 2008.
·Registration No.: 10-0921959-0000; Registration Date: 08. Oct. 2009.
·Korean application No.:KR10-2004-0062070/Filing Date: 06 Aug. 2004.
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